From a performance perspective, the use of transactions is not free. Depending on how you configure them, transaction commits usually require your application to perform disk I/O that a non-transactional application does not perform. Also, for multi-threaded applications, the use of transactions can result in increased lock contention due to extra locking requirements driven by transactional isolation guarantees.
There is therefore a performance tuning component to transactional applications that is not applicable for non-transactional applications (although some tuning considerations do exist whether or not your application uses transactions). Where appropriate, these tuning considerations are introduced in the following chapters.